エーザイ（4523） – Notification Regarding Revision of Consolidated Financial Forecasts (IFRS) for the Fiscal Year Ending March 31, 2023

FOR IMMEDIATE RELEASE June 8, 2022 Listed Company Name: Eisai Co., Ltd. Representative: Haruo Naito Representative Corporate Officer and CEO Securities Code: 4523 Stock Exchange Listings: Prime Market of the Tokyo Stock Exchange Sayoko Sasaki Vice President, Chief IR Officer Stakeholder Communications Phone +81-3-3817-5120 Inquiries: Notification Regarding Revision of Consolidated Financial Forecasts (IFRS) for the Fiscal Year Ending March 31, 2023 Eisai Co., Ltd. (“the Company”) announced today that based on trends in business results, etc., the Company has revised its consolidated financial forecasts for the fiscal year ending March 31, 2023 (April 1, 2022 to March 31, 2023) previously announced on May 13, 2022, as follows. 1. Revised consolidated financial forecasts for the fiscal year ending March 31, 2023 (April 1, 2022 to March 31, 2023) Revenue Operating profit Profit for the year (Unit: Millions of yen, unless otherwise noted.) Profit before income taxes Profit attributable to owners of the parent Basic earnings per share 700,000 55,000 55,500 46,500 45,500 158.85 yen 700,000 55,000 56,500 58,000 57,000 197.80 yen Change in amount (B – A) 1,000 11,500 11,500 Percentage of change (%) 1.8% 24.7% 25.3% – – Previously announced forecast (A) (May 13, 2022) Currently revised forecast (B) (Reference) Business results for the fiscal year ended March 31, 2022 – – 756,226 53,750 54,458 45,717 47,954 167.27 yen 2. Reason for revision of the consolidated financial forecasts In this fiscal year, the Company expects to recognize ¥1.0 billion which is a gain from the transfer of some shares held by the Company. In addition, income taxes are forecasted to be lower than the previous assumption due to the Company’s recognition of losses on sale of investments in subsidiaries for tax purposes following a repayment of paid-in capital from a U.S. subsidiary to the Company in order to collect capital from the U.S. subsidiary as part of the Company’s capital policy to optimize the global allocation of cash in the Company. As a result, the Company has revised profit for the year forecast to ¥58.0 billion, up ¥11.5 billion from the previous forecast, and profit attributable to owners of the parent forecast to ¥57.0 billion yen, up ¥11.5 billion yen from the previous forecast. ROE (Return on Equity attributable to owners of the parent) is expected to be 7.5%. There is no change from the previous forecast for revenue and operating profit. The annual dividend forecast remains unchanged at ¥160 per share (¥80 per share at the end of the second quarter and ¥80 per phare at the end of the fiscal year). * Please note that actual business results may change due to several factors since the above-mentioned forecasts were made based on information available as of June 8, 2022. *** 2