中外製薬（4519） – Notice Regarding the Difference of Individual Financial Results as Compared to Actual Results for the Previous Year

February 3, 2022 Name of listed company: Chugai Pharmaceutical Co., Ltd. Code number: Head office: 4519 (1st Section of Tokyo Stock Exchange) 1-1, Nihonbashi-Muromachi 2-Chome, Chuo-ku, Tokyo President & CEO: Osamu Okuda Inquiries to: Toshiya Sasai Head of Corporate Communications Dept. Tel: +81-(0)3-3273-0554 Notice Regarding the Difference of Individual Financial Results as Compared to Actual Results for the Previous Year Chugai Pharmaceutical Co., Ltd. hereby announces that there is a difference regarding the individual financial results (Japanese standard) for the year ended December 2021 (Jan. 1, 2021 – Dec. 31, 2021) as compared to the actual results for the previous year (Jan. 1, 2020 – Dec. 31, 2020). 1. Difference between the actual results for the year ended December 2021 and the actual results for the previous year Actual results for the previous year (A) (Jan. 1, 2020 – Dec. 31, 2020) Actual results for this year (B) (Jan. 1, 2021 – Dec. 31, 2021) Revenues Operating Income Ordinary Income Net Income Earnings per Share (millions of yen) 779,194 (millions of yen) 288,109 (millions of yen) 290,823 (millions of yen) 207,795 (Yen Sen) 126.44 (millions of yen) 993,350 (millions of yen) 410,313 (millions of yen) 414,116 (millions of yen) 294,713 (Yen Sen) 179.25 Change（B-A） Change（%） (millions of yen) 214,156 27.5 (millions of yen) 122,204 42.4 (millions of yen) 123,293 42.4 (millions of yen) 86,918 41.8 – – 2. Reasons for the difference occurring The difference occurred mainly due to the strong performance of new products and mainstay products in the domestic market, increases in exports to Roche and related royalty and profit-sharing income, and improvement in cost to sales ratio due to changes in product mix, etc. ###